Firefighters were called to the 6,000-square-foot 139 Hartford Road home in Manchester just before 1 a.m. Crews from multiple companies battled the blaze for 40 minutes before getting the flames under control, Manchester authorities said.
No one was injured, but the home was left uninhabitable. The Red Cross is assisting the family.
Known as the Seth Cheney House, the Manchester home was designed by famed historic architect Charles Adams Platt. In 2022, the nine-bedroom house was sold for $635,000.
As news leaked out about the severity of the fire, Manchester residents posted their shock over the loss.
"A work of art is gone!," one woman posted on the Manchester Fire Department's Facebook page.
"Such a historic loss for Manchester and the owners," wrote another.
Authorities are investigating the cause of the fire.
Correction: A previous version of this article incorrectly stated Seth Cheney House was a bed and breakfast after 2022.
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